流感病毒的分子进化

时间：2008.10.14上午8：30

地点：动物科技学院2#楼302房间

报告人简介：

刘文军，研究员、博士生导师。1996年毕业于美国佛罗里达大学，分子和细胞生物学专业，获博士学位；1996-2000年分别于美国Oklahoma大学医学中心和美哈佛休斯医学研究所从事科学研究；2000-2004年任美国GENZYME 公司高级科学家和美国医疗资源有限公司副总裁；2004年入选中国科学院“百人计划”，并获百人计划择优支持。现任中国科学院微生物研究所分子病毒中心主任，中日联合实验室主任等职。目前主持973、十一五支撑计划等多项国家级课题及国际合作项目，主要致力于动物病毒分子进化、禽流感病毒跨种间传播机制以及新型抗病毒药物的研究。

Selected Publications:

1.         Qin Z, Sun L, Ma B, Cui Z, Zhu Y, Kitamura Y, Liu W.F#. F gene recombination between genotype II and VII Newcastle disease virus. Virus Research. 2008 Feb;131(2):299-303.

2.         Sun L, Zhang GH, Jiang JW, Fu JD, Ren T, Cao WS, Xin CA, Liao M, Liu WJ#. A Massachusetts prototype like coronavirus isolated from wild peafowls is pathogenic to chickens. Virus Research. 2007 Dec;130(1-2):121-8.

3.         Yang LM, Xue QH, Sun L, Zhu YP, Liu WJ#. Cloning and characterization of a novel feline IFN-omega. Journal of Interferon Cytokine Research. 2007 Feb;27(2):119-27.

4.         Yang LM, Zhao LZ, Hu RL, Shi ZS, Liu WJ#.A novel double-antigen sandwich enzyme-linked immunosorbent assay for Measurement of Antibodies against rabies virus. Clinical Vaccine Immunology. 2006 Aug;13(8):966-8.

5.         Jinhua Liu, Haixia Xiao, Fumin Lei, Qingyu Zhu, Kun Qin, Xiaowei Zhang, Xinglin Zhang, Deming Zhao, Guihua Wang, Youjun Feng, Juncai Ma, Wenjun Liu, Jian Wang, George F. Gao. Highly pathogenic H5N1 influenza virus infection in migratory birds. Science. 2005,309:5738.

6.         Liu, W.-J., Petier M.R .and Hansen, P. J. (1999) Binding of Ovine Uterine Serpin to Lymphocytes. American Journal of Reproductive Immunology. 41:428.

7.         Ramachdran, R., Nollert M. U., Qiu, H., Liu, W-J., Cummings, R. D., Zhu, C., and McEver, R. P. (1999) Tyrosine replacement in P-selectin glycoprotein ligand-1 affects distinct kinetic and mechanical properties of bonds with P-and E-selectin. Proceedings of National Academy of Sciences of the United States of America. 96:13771.

8.         Liu, W.-J., Ramachdran, R., Kang, J., Cummings, R. D., McEver, R. P. (1998) Identification of N-terminal residues on P-selectin glycoprotein ligand-1 required for binding to P-selectin. Journal of Biological Chemistry. 273:7078.

9.         Liu, W.-J., Gottshall, S. L., and Hansen, P. J. (1997) Increased expression of cell surface markers on / TCR+ intraepithelial lymphocytes by the local presence of the conceptus. American Journal of Reproductive Immunology. 37:199

10.     Liu, W.-J., and Hansen, P. J. (1995) Progesterone-induced secretion of a soluble form of dipeptidyl peptidase IV (CD26) by the uterine endometrium of the ewe and cow that costimulates lymphocyte proliferation. Endocrinology. 136:779